

| VWD Info & List of Clears |
| We will soon have a lot more information here for you concerning vWD or von Willebrand’s as it is formally known. This is a bleeding disorder that some Dobermans can be affected with and make surgeries and such deadly unless planned out carefully before hand. More information will be posted soon from a research paper being done by one of our members until then VetGen kindly let us include the following information for you to read over and hopefully understand the results and what to do about breeding your doberman a lot better. Interpreting Your DNA Test Results… -------------------------------------------------------------------------------- There are three possible test results: Clear, Carrier, and Affected. Below is a description of what each result means to you as a breeder. CLEAR This finding indicates that the gene is not present in your dog. Therefore, when used for breeding, a Clear dog will not pass on the disease gene. CARRIER This finding indicates that one copy of the disease gene is present in your dog, but that it will not exhibit disease symptoms. Carriers will not have medical problems as a result. Dogs with Carrier status can be enjoyed without the fear of developing medical problems but will pass on the disease gene 50% of the time. AFFECTED This finding indicates that two copies of the disease gene are present in the dog. Unfortunately, the dog will be medically affected by the disease. Appropriate treatment should be pursued by consulting a veterinarian. Breeding Strategies… -------------------------------------------------------------------------------- VetGen's DNA test findings can be extremely valuable when developing and implementing your breeding plans. The chart provided below outlines the implications of various breeding pair combinations. Remember, it is always best to breed "Clear to Clear". If followed by all breeders, these strategies will ensure a significant reduction in the frequency of the targeted disease gene in future generations of dogs. However, to maintain a large enough pool of good breeding stock, it may be necessary for some breeders to breed "Clear" to "Carriers" (see below). Breeding Pair Combinations: Breeding Clear to Clear results in Clear Puppies Breeding Clear to Carrier results in 50% Carrier and 50 % Clear Puppies Breeding Clear to Affected results in All Carrier Puppies Breeding Carrier to Carrier results in Affeted, Carrier and Clear Puppies Breeding Carrier to Affected results in 50% Carrier and 50% Affected Puppies Breeding Affected to Affected results in all puppies Affected Ideal Breeding Pair is clear to clear: Puppies will not have the disease gene (neither as Carrier nor as Affected). It is recommended to DNA for vWD to know the status of your dog and breed wisely |